There are many things you could do with this idea. My idea is as follows...
Various people each week are tasked with finding an opponent to have a grudge match against. At the end of a set number of weeks the winners of each of the grudge matches face off in a single elimination tournament with the winner crowned gladiator (or something). Then the process could repeat itself.
Of course there doesn't have to be a tournament at the end, I just liked the idea of the grudge match winners facing off against each other.
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